BDBM616336 3,5-dichloro-N-(2,8-dimethyl-4- oxo-3-(2- (trifluoromethyl)benzyl)-3,4- dihydroquinazolin-5-yl)-4- hydroxybenzamide::US20230278981, Example 151::US20230278981, Example 179::US20230278981, Example 200

SMILES Cc1ccc(NC(=O)c2cc(Cl)c(O)c(Cl)c2)c2c1nc(C)n(Cc1ccccc1C(F)(F)F)c2=O

InChI Key InChIKey=VWLKLPGOFPETDX-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 616336   

Target17-beta-hydroxysteroid dehydrogenase 13(Human)
Inipharm

US Patent
LigandPNGBDBM616336(US20230278981, Example 151 | US20230278981, Exampl...)
Affinity DataIC50: 100nMAssay Description:Reactions were terminated by the addition of two volumes of acetonitrile (MeCN; LCMS grade; CAS #75/05/8) containing deuterated (D4)-E1 used as inter...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/18/2023
Entry Details
US Patent

Target17-beta-hydroxysteroid dehydrogenase 13(Human)
Inipharm

US Patent
LigandPNGBDBM616336(US20230278981, Example 151 | US20230278981, Exampl...)
Affinity DataIC50: 100nMAssay Description:Reactions were terminated by the addition of two volumes of acetonitrile (MeCN; LCMS grade; CAS #75/05/8) containing deuterated (D4)-E1 used as inter...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/18/2023
Entry Details
US Patent

Target17-beta-hydroxysteroid dehydrogenase 13(Human)
Inipharm

US Patent
LigandPNGBDBM616336(US20230278981, Example 151 | US20230278981, Exampl...)
Affinity DataIC50: 100nMAssay Description:Reactions were terminated by the addition of two volumes of acetonitrile (MeCN; LCMS grade; CAS #75/05/8) containing deuterated (D4)-E1 used as inter...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/18/2023
Entry Details
US Patent