BDBM616878 US20230279024, Example 32

SMILES Nc1ncnn2c(C3CCC(O)CC3)cc(-c3ccc(NC(=O)c4c5n(n(-c6ccccn6)c4=O)CCOC5)cc3)c12

InChI Key InChIKey=OCQPGLWJKKQMFH-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 616878   

TargetTyrosine-protein kinase receptor UFO(Human)
Beijing Findcure Biosciences

US Patent
LigandChemical structure of BindingDB Monomer ID 616878BDBM616878(US20230279024, Example 32)
Affinity DataIC50: 5nMAssay Description:The effect of the disclosed compounds as protein kinase inhibitors can be evaluated by the following experiments. The AXL (h) kinase activity of the ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/17/2023
Entry Details
US Patent