BDBM616889 2-(5-(cyclopropylmethyl)-3-(6-fluoro-4'-(trifluoromethyl)- 2',3',4',5'-tetrahydro-[1,1'-biphenyl]-3-yl)-4-(3-fluoro-4- sulfamoylbenzyl)-1H-pyrazol-1-yl)thiazole-4-carboxylic acid::US11752138, Compound 102

SMILES NS(=O)(=O)c1ccc(Cc2c(CC3CC3)n(nc2-c2ccc(F)c(c2)C2=CCC(CC2)C(F)(F)F)-c2nc(cs2)C(O)=O)cc1F

InChI Key InChIKey=GYHPBZVCJVWUBH-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 616889   

TargetL-lactate dehydrogenase B chain(Human)
Vanderbilt University

US Patent
LigandPNGBDBM616889(US11752138, Compound 102 | 2-(5-(cyclopropylmethyl...)
Affinity DataIC50: 100nMAssay Description:This example describes a human LDHB biochemical assay employed in the characterization of a compound of Formula I in an embodiment of the dislcosure....More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/20/2023
Entry Details
US Patent