BDBM616924 2-(5-(cyclopropylmethyl)-3-(6-fluoro-4'-(trifluoromethyl)- [1,1'-biphenyl]-3-yl)-4-(3-fluoro-4-sulfamoylbenzyl)-1H- pyrazol-1-yl)thiazole-4-carboxylic acid::US11752138, Compound 138

SMILES NS(=O)(=O)c1ccc(Cc2c(CC3CC3)n(nc2-c2ccc(F)c(c2)-c2ccc(cc2)C(F)(F)F)-c2nc(cs2)C(O)=O)cc1F

InChI Key InChIKey=WBJPOGLPMUBIBW-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 616924   

TargetL-lactate dehydrogenase B chain(Human)
Vanderbilt University

US Patent
LigandPNGBDBM616924(US11752138, Compound 138 | 2-(5-(cyclopropylmethyl...)
Affinity DataIC50: 100nMAssay Description:This example describes a human LDHB biochemical assay employed in the characterization of a compound of Formula I in an embodiment of the dislcosure....More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/20/2023
Entry Details
US Patent