BDBM616937 2-(3-(3'-chloro-6-fluoro-[1,1'-biphenyl]-3-yl)-5- (cyclopropylmethyl)-4-(3-fluoro-4-sulfamoylbenzyl)-1H- pyrazol-1-yl)thiazole-4-carboxylic acid::US11752138, Compound 149

SMILES NS(=O)(=O)c1ccc(Cc2c(CC3CC3)n(nc2-c2ccc(F)c(c2)-c2cccc(Cl)c2)-c2nc(cs2)C(O)=O)cc1F

InChI Key InChIKey=QLVMKYZRTQCAQW-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 616937   

TargetL-lactate dehydrogenase B chain(Human)
Vanderbilt University

US Patent
LigandPNGBDBM616937(US11752138, Compound 149 | 2-(3-(3'-chloro-6-fluor...)
Affinity DataIC50: 100nMAssay Description:This example describes a human LDHB biochemical assay employed in the characterization of a compound of Formula I in an embodiment of the dislcosure....More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/20/2023
Entry Details
US Patent