BDBM617448 US20230285377, Example 32

SMILES C[C@@H](NC(=O)c1cccc(c1)C(F)(F)F)c1cc(no1)-c1ccnc(c1)C(F)(F)F

InChI Key InChIKey=PHEWVRMDJVESLV-SNVBAGLBSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 617448   

TargetPotassium channel subfamily T member 1(Homo sapiens)
Praxis Precision Medicines

US Patent
LigandPNGBDBM617448(US20230285377, Example 32)
Affinity DataIC50: <1.00E+3nMAssay Description:Inhibition of KCNT1 (KNa1.1, Slack) was evaluated using a tetracycline inducible cell line (HEK-TREX). Currents were recorded using the SyncroPatch 3...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent