BDBM617480 N-((2-chloro-4-((3-(3,3-dimethylbutyl)-4-oxo-3,4-dihydroquinazolin-5-yl)carbamoyl)phenyl)sulfonyl)nicotinamide::US20230286923, Example 16

SMILES CC(C)(C)CCn1cnc2cccc(NC(=O)c3ccc(c(Cl)c3)S(=O)(=O)NC(=O)c3cccnc3)c2c1=O

InChI Key InChIKey=HXGMUSXVWYHSPY-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 617480   

Target17-beta-hydroxysteroid dehydrogenase 13(Human)
Inipharm

US Patent
LigandPNGBDBM617480(US20230286923, Example 16 | N-((2-chloro-4-((3-(3,...)
Affinity DataIC50: 7.50E+3nMAssay Description:The liquid chromatography/mass spectrometry (LC/MS) estrone detection assay monitors the conversion of estradiol to estrone by HSD17B13. This assay w...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/23/2023
Entry Details
US Patent