BDBM617577 US20230286943, Example 45

SMILES CCn1nccc1C(=O)N[C@H](C(=O)Nc1ccc(-c2c(C)cnn2C)cn1)[C@H]1CC[C@H](C)CC1

InChI Key InChIKey=CLQAAYZHCVVKBK-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 617577   

TargetInterleukin-17F(Human)
Sanofi

US Patent
LigandChemical structure of BindingDB Monomer ID 617577BDBM617577(US20230286943, Example 45)
Affinity DataIC50: 50.1nMAssay Description:The ability of the compounds to block binding of IL-17A to its receptor, IL-17RA, was analysed in a competition assay using AlphaLISA technology (Per...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/23/2023
Entry Details
US Patent