BDBM618082 US20230286970, Compound 25

SMILES Oc1ccc(cc1NC(=O)N1CCOCC1)-c1nnn(Cc2ccc(cc2)-c2nnc(o2)C(F)F)n1

InChI Key InChIKey=NGHQATVBLURDPD-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 618082   

TargetHistone deacetylase 6(Human)
Italfarmaco

US Patent
LigandPNGBDBM618082(US20230286970, Compound 25)
Affinity DataIC50: 7nMAssay Description:For each test compound, 100× concentrated DMSO solutions at 8 doses were prepared and then diluted in assay buffer (25 mM Tris-HCl, pH 8, 130 mM NaCl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/23/2023
Entry Details
US Patent

TargetHistone deacetylase 1(Human)
Italfarmaco

US Patent
LigandPNGBDBM618082(US20230286970, Compound 25)
Affinity DataIC50: 2.00E+5nMAssay Description:For each test compound, 100× concentrated DMSO solutions at 8 doses were prepared and then diluted in assay buffer (25 mM Tris-HCl, pH 8, 130 mM NaCl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/23/2023
Entry Details
US Patent