BDBM618086 7'-(2-((5-(5-(difluoromethyl)-1,3,4-oxadiazol-2-yl)pyridin-2-yl)methyl)-2H-tetrazol-5-yl)-1',4'-dihydro-3'H-spiro[cyclopentane-1,2'-quinoxalin]-3'-one::US20230286970, Compound 27

SMILES FC(F)c1nnc(o1)-c1ccc(Cn2nnc(n2)-c2ccc3NC(=O)C4(CCCC4)Nc3c2)nc1

InChI Key InChIKey=QTJLLWZXGSKPOJ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 618086   

TargetHistone deacetylase 6(Human)
Italfarmaco

US Patent
LigandPNGBDBM618086(US20230286970, Compound 27 | 7'-(2-((5-(5-(difluor...)
Affinity DataIC50: 9nMAssay Description:For each test compound, 100× concentrated DMSO solutions at 8 doses were prepared and then diluted in assay buffer (25 mM Tris-HCl, pH 8, 130 mM NaCl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/23/2023
Entry Details
US Patent

TargetHistone deacetylase 1(Human)
Italfarmaco

US Patent
LigandPNGBDBM618086(US20230286970, Compound 27 | 7'-(2-((5-(5-(difluor...)
Affinity DataIC50: 2.00E+5nMAssay Description:For each test compound, 100× concentrated DMSO solutions at 8 doses were prepared and then diluted in assay buffer (25 mM Tris-HCl, pH 8, 130 mM NaCl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/23/2023
Entry Details
US Patent