BDBM618105 7'-(1-((5-(5-(difluoromethyl)-1,3,4-oxadiazol-2-yl)pyridin-2-yl)methyl)-1H-1,2,3-triazol-4-yl)-1',4'-dihydro-3'H-spiro[piperidine-4,2'-quinoxalin]-3'-one::US20230286970, Compound 36

SMILES FC(F)c1nnc(o1)-c1ccc(Cn2cc(nn2)-c2ccc3NC(=O)C4(CCNCC4)Nc3c2)nc1

InChI Key InChIKey=YVLGPWANSNJRDS-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 618105   

TargetHistone deacetylase 6(Human)
Italfarmaco

US Patent
LigandPNGBDBM618105(US20230286970, Compound 36 | 7'-(1-((5-(5-(difluor...)
Affinity DataIC50: 16nMAssay Description:For each test compound, 100× concentrated DMSO solutions at 8 doses were prepared and then diluted in assay buffer (25 mM Tris-HCl, pH 8, 130 mM NaCl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/23/2023
Entry Details
US Patent

TargetHistone deacetylase 1(Human)
Italfarmaco

US Patent
LigandPNGBDBM618105(US20230286970, Compound 36 | 7'-(1-((5-(5-(difluor...)
Affinity DataIC50: 2.00E+5nMAssay Description:For each test compound, 100× concentrated DMSO solutions at 8 doses were prepared and then diluted in assay buffer (25 mM Tris-HCl, pH 8, 130 mM NaCl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/23/2023
Entry Details
US Patent