BDBM618157 US20230286970, Compound 276

SMILES FC(F)c1nnc(o1)-c1ccc(Cn2nnc(n2)-c2cccc(c2)-c2nc3CNCCc3[nH]2)nc1

InChI Key InChIKey=XMQUTLMCBXHACO-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 618157   

TargetHistone deacetylase 6(Human)
Italfarmaco

US Patent
LigandPNGBDBM618157(US20230286970, Compound 276)
Affinity DataIC50: 9nMAssay Description:For each test compound, 100× concentrated DMSO solutions at 8 doses were prepared and then diluted in assay buffer (25 mM Tris-HCl, pH 8, 130 mM NaCl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/23/2023
Entry Details
US Patent

TargetHistone deacetylase 1(Human)
Italfarmaco

US Patent
LigandPNGBDBM618157(US20230286970, Compound 276)
Affinity DataIC50: 1.65E+5nMAssay Description:For each test compound, 100× concentrated DMSO solutions at 8 doses were prepared and then diluted in assay buffer (25 mM Tris-HCl, pH 8, 130 mM NaCl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/23/2023
Entry Details
US Patent