BDBM618221 5-[1-[[5-[5-(difluoromethyl)-1,3,4-oxadiazol-2-yl]pyridin-2-yl]methyl]imidazol-4-yl]-1,3-benzoxazol-2-amine::US20230286970, Compound 308

SMILES Nc1nc2cc(ccc2o1)-c1cn(Cc2ccc(cn2)-c2nnc(o2)C(F)F)cn1

InChI Key InChIKey=VKYRLORYVVZGFM-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 618221   

TargetHistone deacetylase 6(Human)
Italfarmaco

US Patent
LigandPNGBDBM618221(US20230286970, Compound 308 | 5-[1-[[5-[5-(difluor...)
Affinity DataIC50: 15nMAssay Description:For each test compound, 100× concentrated DMSO solutions at 8 doses were prepared and then diluted in assay buffer (25 mM Tris-HCl, pH 8, 130 mM NaCl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/23/2023
Entry Details
US Patent

TargetHistone deacetylase 1(Human)
Italfarmaco

US Patent
LigandPNGBDBM618221(US20230286970, Compound 308 | 5-[1-[[5-[5-(difluor...)
Affinity DataIC50: 1.00E+6nMAssay Description:For each test compound, 100× concentrated DMSO solutions at 8 doses were prepared and then diluted in assay buffer (25 mM Tris-HCl, pH 8, 130 mM NaCl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/23/2023
Entry Details
US Patent