BDBM618249 US20230286970, Compound 322

SMILES Nc1nc2cc(ccc2s1)-c1cn(Cc2ccc(cn2)-c2nnc(o2)C(F)F)cn1

InChI Key InChIKey=KVBUHEWKZBRRLL-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 618249   

TargetHistone deacetylase 6(Human)
Italfarmaco

US Patent
LigandPNGBDBM618249(US20230286970, Compound 322)
Affinity DataIC50: 17nMAssay Description:For each test compound, 100× concentrated DMSO solutions at 8 doses were prepared and then diluted in assay buffer (25 mM Tris-HCl, pH 8, 130 mM NaCl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/23/2023
Entry Details
US Patent

TargetHistone deacetylase 1(Human)
Italfarmaco

US Patent
LigandPNGBDBM618249(US20230286970, Compound 322)
Affinity DataIC50: 1.00E+6nMAssay Description:For each test compound, 100× concentrated DMSO solutions at 8 doses were prepared and then diluted in assay buffer (25 mM Tris-HCl, pH 8, 130 mM NaCl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/23/2023
Entry Details
US Patent