BDBM618472 US20230286978, Example 8

SMILES C[C@H](NC(=O)c1cccc2c(n[nH]c12)-c1ccncc1)c1ccc(Cl)cc1

InChI Key InChIKey=VXJQYPXWIRIBPI-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 618472   

TargetNAD(+) hydrolase SARM1(Human)
Disarm Therapeutics

US Patent
LigandPNGBDBM618472(US20230286978, Example 8)
Affinity DataIC50: 1.00E+4nMAssay Description:The enzymatic assay was performed in a 384-well polypropylene plate in Dulbecco s PBS buffer in a final assay volume of 20 µL. ARM-SAM-TIR lysate wit...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/23/2023
Entry Details
US Patent