BDBM618635 US11760752, Compound 52

SMILES Cc1cc(Oc2ccc(Cn3nc(C(=O)NS(=O)(=O)Cc4ccc(NCc5cccnc5)c(c4)[N+]([O-])=O)c4cc(Cl)ccc34)cc2)cc(C)c1Cl

InChI Key InChIKey=WDUNBTMJOAQXDC-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 618635   

TargetApoptosis regulator Bcl-2(Human)
University of Maryland, Baltimore

US Patent
LigandPNGBDBM618635(US11760752, Compound 52)
Affinity DataKi:  690nMAssay Description:The fluorescence polarization assays were performed in 96 well polypropylene F-bottom black microplates (Greiner Bio-One) with a final volume of 100 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/29/2023
Entry Details
US Patent

TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Human)
University of Maryland, Baltimore

US Patent
LigandPNGBDBM618635(US11760752, Compound 52)
Affinity DataKi: >1.00E+4nMAssay Description:The fluorescence polarization assays were performed in 96 well polypropylene F-bottom black microplates (Greiner Bio-One) with a final volume of 100 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/29/2023
Entry Details
US Patent