BDBM618914 4-Cyano-N-[4-(3-cyanophenyl)-5-[2-(1-hydroxy-1-methyl-ethyl)-6-methyl-4-pyridyl]thiazol-2-yl]-4-methyl-piperidine-1-carboxamide::US20230293517, Example 12

SMILES Cc1cc(cc(n1)C(C)(C)O)-c1sc(NC(=O)N2CCC(C)(CC2)C#N)nc1-c1cccc(c1)C#N

InChI Key InChIKey=UBPOFNRPXJPSTC-UHFFFAOYSA-N

Data  4 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 618914   

TargetAdenosine receptor A2a(Homo sapiens (Human))
Adorx Therapeutics

US Patent
LigandPNGBDBM618914(4-Cyano-N-[4-(3-cyanophenyl)-5-[2-(1-hydroxy-1-met...)
Affinity DataKi:  0.160nMAssay Description:All FRET binding experiments were conducted at room temperature in white 384-well plates, in assay binding buffer containing 1×LabMed (Cisbio, France...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAdenosine receptor A2b(Homo sapiens (Human))
Adorx Therapeutics

US Patent
LigandPNGBDBM618914(4-Cyano-N-[4-(3-cyanophenyl)-5-[2-(1-hydroxy-1-met...)
Affinity DataKi:  3.10nMAssay Description:All FRET binding experiments were conducted at room temperature in white 384-well plates, in assay binding buffer containing 1×LabMed (Cisbio, France...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAdenosine receptor A1(Homo sapiens (Human))
Adorx Therapeutics

US Patent
LigandPNGBDBM618914(4-Cyano-N-[4-(3-cyanophenyl)-5-[2-(1-hydroxy-1-met...)
Affinity DataKi:  6nMAssay Description:All FRET binding experiments were conducted at room temperature in white 384-well plates, in assay binding buffer containing 1×LabMed (Cisbio, France...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAdenosine receptor A3(Homo sapiens (Human))
Adorx Therapeutics

US Patent
LigandPNGBDBM618914(4-Cyano-N-[4-(3-cyanophenyl)-5-[2-(1-hydroxy-1-met...)
Affinity DataKi:  930nMAssay Description:All FRET binding experiments were conducted at room temperature in white 384-well plates, in assay binding buffer containing 1×LabMed (Cisbio, France...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent