BDBM618966 N-[5-[2,6-Bis(trideuteriomethyl)-4-pyridyl]-4-(3-cyanophenyl)thiazol-2-yl]-4-cyano-4-methyl-piperidine-1-carboxamide::US20230293517, Example 28

SMILES [2H]C([2H])([2H])c1cc(cc(n1)C([2H])([2H])[2H])-c1sc(NC(=O)N2CCC(C)(CC2)C#N)nc1-c1cccc(c1)C#N

InChI Key InChIKey=PFFKSQAULAQWHE-WFGJKAKNSA-N

Data  4 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 618966   

TargetAdenosine receptor A2a(Human)
Adorx Therapeutics

US Patent
LigandPNGBDBM618966(N-[5-[2,6-Bis(trideuteriomethyl)-4-pyridyl]-4-(3-c...)
Affinity DataKi:  0.0900nMAssay Description:All FRET binding experiments were conducted at room temperature in white 384-well plates, in assay binding buffer containing 1×LabMed (Cisbio, France...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent


TargetAdenosine receptor A2b(Human)
Adorx Therapeutics

US Patent
LigandPNGBDBM618966(N-[5-[2,6-Bis(trideuteriomethyl)-4-pyridyl]-4-(3-c...)
Affinity DataKi:  1nMAssay Description:All FRET binding experiments were conducted at room temperature in white 384-well plates, in assay binding buffer containing 1×LabMed (Cisbio, France...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent


TargetAdenosine receptor A1(Human)
Adorx Therapeutics

US Patent
LigandPNGBDBM618966(N-[5-[2,6-Bis(trideuteriomethyl)-4-pyridyl]-4-(3-c...)
Affinity DataKi:  30nMAssay Description:All FRET binding experiments were conducted at room temperature in white 384-well plates, in assay binding buffer containing 1×LabMed (Cisbio, France...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent


TargetAdenosine receptor A3(Human)
Adorx Therapeutics

US Patent
LigandPNGBDBM618966(N-[5-[2,6-Bis(trideuteriomethyl)-4-pyridyl]-4-(3-c...)
Affinity DataKi:  381nMAssay Description:All FRET binding experiments were conducted at room temperature in white 384-well plates, in assay binding buffer containing 1×LabMed (Cisbio, France...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent