BDBM618972 US20230295110, Compound 6

SMILES Cc1c(O)c(ncc1-c1cnn(c1)C1CCN(CC1)C(=O)OC(C)(C)C)C(=O)NCC(O)=O

InChI Key InChIKey=HXNZJRFVQLJEBY-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 618972   

TargetEgl nine homolog 1(Human)
Akebia Therapeutics

US Patent
LigandPNGBDBM618972(US20230295110, Compound 6)
Affinity DataIC50: 100nMAssay Description:Time-resolved fluorescence resonance energy transfer (TR-FRET) assay was utilized to determine the enzymatic half maximal inhibitory concentration (I...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2023
Entry Details
US Patent

TargetProlyl hydroxylase EGLN2(Human)
Akebia Therapeutics

US Patent
LigandPNGBDBM618972(US20230295110, Compound 6)
Affinity DataIC50: 100nMAssay Description:Time-resolved fluorescence resonance energy transfer (TR-FRET) assay was utilized to determine the enzymatic half maximal inhibitory concentration (I...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2023
Entry Details
US Patent