BDBM619632 (Z)-6-((2-(aminomethyl)-3-fluoroallyl)oxy)-N-((6-(trifluoromethyl)pyridin-3-yl)methyl)benzo[d]oxazol-2-amine 4-methylbenzenesulfonate::US11787791, Example 83::US20230295140, Example 83

SMILES NC\C(COc1ccc2nc(NCc3ccc(nc3)C(F)(F)F)oc2c1)=C\F

InChI Key InChIKey=GMESSFBNXUMNCB-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 619632   

TargetAmine oxidase [copper-containing] 3(Human)
Acucela

US Patent
LigandPNGBDBM619632(US20230295140, Example 83 | US11787791, Example 83...)
Affinity DataIC50: 100nMAssay Description:The capability of compounds described herein to inhibit the enzymatic activity of vascular adhesion protein-1 (VAP-1) was determined by fluorometric ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2023
Entry Details
US Patent

TargetAmine oxidase [copper-containing] 3(Human)
Acucela

US Patent
LigandPNGBDBM619632(US20230295140, Example 83 | US11787791, Example 83...)
Affinity DataIC50: 100nMAssay Description:The capability of compounds described herein to inhibit the enzymatic activity of vascular adhesion protein-1 (VAP-1) was determined by fluorometric ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/29/2023
Entry Details
US Patent

TargetAmine oxidase [flavin-containing] B(Human)
Acucela

US Patent
LigandPNGBDBM619632(US20230295140, Example 83 | US11787791, Example 83...)
Affinity DataIC50: 5.50E+3nMAssay Description:The capability of compounds described herein to inhibit MAO was determined using a modified Promega MAO-Glo assay kit. The substrate ((4S)-4,5-dihydr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/29/2023
Entry Details
US Patent

TargetAmine oxidase [flavin-containing] B(Human)
Acucela

US Patent
LigandPNGBDBM619632(US20230295140, Example 83 | US11787791, Example 83...)
Affinity DataIC50: 5.50E+3nMAssay Description:The capability of compounds described herein to inhibit MAO was determined using a modified Promega MAO-Glo assay kit. The substrate ((4S)-4,5-dihydr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2023
Entry Details
US Patent

TargetAmine oxidase [flavin-containing] A(Human)
Acucela

US Patent
LigandPNGBDBM619632(US20230295140, Example 83 | US11787791, Example 83...)
Affinity DataIC50: 2.00E+4nMAssay Description:The capability of compounds described herein to inhibit MAO was determined using a modified Promega MAO-Glo assay kit. The substrate ((4S)-4,5-dihydr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/29/2023
Entry Details
US Patent

TargetAmine oxidase [flavin-containing] A(Human)
Acucela

US Patent
LigandPNGBDBM619632(US20230295140, Example 83 | US11787791, Example 83...)
Affinity DataIC50: 2.00E+4nMAssay Description:The capability of compounds described herein to inhibit MAO was determined using a modified Promega MAO-Glo assay kit. The substrate ((4S)-4,5-dihydr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2023
Entry Details
US Patent