BDBM620078 2-(5-(3-((5-cyano-4-(4-fluorophenyl)thiazol-2-yl)(methyl)amino)-2-ethylimidazo[1,2-a]pyridin-6-yl)pyrazin-2-yl)-N-((5-oxopyrrolidin-2-yl)methyl)acetamide ::US20230295159, Example 14

SMILES CCc1nc2ccc(cn2c1N(C)c1nc(c(s1)C#N)-c1ccc(F)cc1)-c1cnc(CC(=O)NCC2CCC(=O)N2)cn1

InChI Key InChIKey=QMPJVBFSGYGUIC-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 620078   

TargetAutotaxin(Human)
Suzhou Ark Biopharmaceutical

US Patent
LigandPNGBDBM620078(2-(5-(3-((5-cyano-4-(4-fluorophenyl)thiazol-2-yl)(...)
Affinity DataIC50: 42nMAssay Description:The tested compounds were dissolved with dimethyl sulfoxide (DMSO) to prepare 20 mM of stock solutions, the stock solutions were subjected to 4-fold ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2023
Entry Details
US Patent