BDBM620082 2-((5-(2-(1,1-dioxidoisothiazolidin-2-yl)pyrimidin-5-yl)-2-ethyl-pyrazolo[1,5-a]pyrimidin-3-yl)(ethyl)amino)-4-(4-fluorophenyl)thiazole-5-carbonitrile ::US20230295159, Example 18

SMILES CCN(c1nc(c(s1)C#N)-c1ccc(F)cc1)c1c(CC)nn2ccc(nc12)-c1cnc(nc1)N1CCCS1(=O)=O

InChI Key InChIKey=KWPFAVUXTWRQIW-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 620082   

TargetAutotaxin(Human)
Suzhou Ark Biopharmaceutical

US Patent
LigandPNGBDBM620082(2-((5-(2-(1,1-dioxidoisothiazolidin-2-yl)pyrimidin...)
Affinity DataIC50: 15nMAssay Description:The tested compounds were dissolved with dimethyl sulfoxide (DMSO) to prepare 20 mM of stock solutions, the stock solutions were subjected to 4-fold ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2023
Entry Details
US Patent