BDBM620083 2-((6-(5-(1,1-dioxidoisothiazolidin-2-yl)pyrazin-2-yl)-2-ethylimidazo[1,2-a]pyridin-3-yl)(ethyl)amino)-4-(4-fluorophenyl)thiazole-5-carbonitrile ::US20230295159, Example 19

SMILES CCN(c1nc(c(s1)C#N)-c1ccc(F)cc1)c1c(CC)nc2ccc(cn12)-c1cnc(cn1)N1CCCS1(=O)=O

InChI Key InChIKey=DYFPTOUGCBISDZ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 620083   

TargetAutotaxin(Human)
Suzhou Ark Biopharmaceutical

US Patent
LigandPNGBDBM620083(2-((6-(5-(1,1-dioxidoisothiazolidin-2-yl)pyrazin-2...)
Affinity DataIC50: 17nMAssay Description:The tested compounds were dissolved with dimethyl sulfoxide (DMSO) to prepare 20 mM of stock solutions, the stock solutions were subjected to 4-fold ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2023
Entry Details
US Patent