BDBM620085 2-((5-(2-(1,1-dioxido-1,2-thiazinan-2-yl)pyrimidin-5-yl)-2-ethyl-2H-pyrazolo[4,3-b]pyridin-3-yl)(ethyl)amino)-4-(4-fluorophenyl)thiazole-5-carbonitrile ::US20230295159, Example 21

SMILES CCN(c1nc(c(s1)C#N)-c1ccc(F)cc1)c1n(CC)nc2ccc(nc12)-c1cnc(nc1)N1CCCCS1(=O)=O

InChI Key InChIKey=GILGLNPMDJCWDZ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 620085   

TargetAutotaxin(Human)
Suzhou Ark Biopharmaceutical

US Patent
LigandPNGBDBM620085(2-((5-(2-(1,1-dioxido-1,2-thiazinan-2-yl)pyrimidin...)
Affinity DataIC50: 11nMAssay Description:The tested compounds were dissolved with dimethyl sulfoxide (DMSO) to prepare 20 mM of stock solutions, the stock solutions were subjected to 4-fold ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2023
Entry Details
US Patent