BDBM620088 1-(5-(3-((5-cyano-4-(4-fluorophenyl)thiazol-2-yl)(ethyl)amino)-2-ethyl-2H-pyrazolo[4,3-b]pyridin-5-yl)pyrimidin-2-yl)azetidin-3-yl Acetate ::US20230295159, Example 25

SMILES CCN(c1nc(c(s1)C#N)-c1ccc(F)cc1)c1n(CC)nc2ccc(nc12)-c1cnc(nc1)N1CC(C1)OC(C)=O

InChI Key InChIKey=ZUAXRNFDBHRSHH-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 620088   

TargetAutotaxin(Human)
Suzhou Ark Biopharmaceutical

US Patent
LigandPNGBDBM620088(1-(5-(3-((5-cyano-4-(4-fluorophenyl)thiazol-2-yl)(...)
Affinity DataIC50: 12nMAssay Description:The tested compounds were dissolved with dimethyl sulfoxide (DMSO) to prepare 20 mM of stock solutions, the stock solutions were subjected to 4-fold ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2023
Entry Details
US Patent