BDBM620113 (1R,5S)-3-(4-(1-(methylsulfonyl)cyclopropyl)-7-(1H-pyrazol-5-yl)imidazo[1,5-b]pyridazin-2-yl)-8-oxa-3-azabicyclo[3.2.1]octane::US20230295166, Compound 32

SMILES CS(=O)(=O)C1(c2cc(N3CC4CCC(C3)O4)nn3c(-c4ccn[nH]4)ncc23)CC1

InChI Key InChIKey=ZIGBKVTUMUTSPK-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 620113   

TargetSerine/threonine-protein kinase ATR(Human)
Antengene Discovery

US Patent
LigandChemical structure of BindingDB Monomer ID 620113BDBM620113((1R,5S)-3-(4-(1-(methylsulfonyl)cyclopropyl)-7-(1H...)
Affinity DataIC50: 100nMAssay Description:Detection of ATR kinase activity utilized the Mobility shift assay to measure the phosphorylation of the substrate protein FAM-RAD17 (GL, Cat. No. 51...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2023
Entry Details
US Patent