BDBM620141 (2R,3R,4S,5R,6R)-2-((1,8-dioxa-2-azaspiro[4.5]dec-2-en-3-yl)methyl)-4-(4- (2,3-difluoro-4-methylphenyl)-1H-1,2,3-triazol-1-yl)-5-hydroxy-6- (hydroxymethyl)tetrahydro-2H-pyran-3-yl acetate::US20230295182, Example 1.01

SMILES CC(=O)O[C@H]1[C@@H](CC2=NOC3(C2)CCOCC3)O[C@H](CO)[C@H](O)[C@@H]1n1cc(nn1)-c1ccc(C)c(F)c1F

InChI Key InChIKey=HURGGBFMJRZMGJ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 620141   

TargetGalectin-3(Human)
Idorsia Pharmaceuticals

US Patent
LigandPNGBDBM620141(US20230295182, Example 1.01 | (2R,3R,4S,5R,6R)-2-(...)
Affinity DataIC50: 61nMAssay Description:Briefly, compounds are serially diluted in DMSO (working dilutions). ASF-coated 384 well plates are supplemented with 22.8 uL/well of biotinylated hG...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2023
Entry Details
US Patent

TargetGalectin-1(Human)
Idorsia Pharmaceuticals

US Patent
LigandPNGBDBM620141(US20230295182, Example 1.01 | (2R,3R,4S,5R,6R)-2-(...)
Affinity DataIC50: 4.20E+3nMAssay Description:Briefly, compounds are serially diluted in DMSO (working dilutions). ASF-coated 384 well plates are supplemented with 22.8 uL/well of biotinylated hG...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2023
Entry Details
US Patent