BDBM620233 US20230295171, Example 125::US20230295171, Example 93

SMILES N[C@H]1COCC[C@H]1Nc1nc(-c2cnn(c2)C(F)F)c2C(=O)NCc2c1F

InChI Key InChIKey=RYADIWBTHCLJOG-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 620233   

TargetTyrosine-protein kinase SYK(Human)
Calithera Biosciences

US Patent
LigandPNGBDBM620233(US20230295171, Example 125 | US20230295171, Exampl...)
Affinity DataIC50: 10nMAssay Description:YK protein is prepared from cDNA encoding human spleen tyrosine kinase and is expressed in insect cells using a baculovirus expression vector. The cD...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2023
Entry Details
US Patent

TargetTyrosine-protein kinase SYK(Human)
Calithera Biosciences

US Patent
LigandPNGBDBM620233(US20230295171, Example 125 | US20230295171, Exampl...)
Affinity DataIC50: 10nMAssay Description:YK protein is prepared from cDNA encoding human spleen tyrosine kinase and is expressed in insect cells using a baculovirus expression vector. The cD...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2023
Entry Details
US Patent