BDBM620252 US20230295171, Example 112::US20230295171, Example 122

SMILES Cc1ncc(s1)-c1nc(N[C@@H]2CCCC[C@@H]2N)c(F)c2CNC(=O)c12

InChI Key InChIKey=XYDQHRTVTJCMOX-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 620252   

TargetTyrosine-protein kinase SYK(Human)
Calithera Biosciences

US Patent
LigandPNGBDBM620252(US20230295171, Example 122 | US20230295171, Exampl...)
Affinity DataIC50: 2nMAssay Description:YK protein is prepared from cDNA encoding human spleen tyrosine kinase and is expressed in insect cells using a baculovirus expression vector. The cD...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2023
Entry Details
US Patent

TargetTyrosine-protein kinase SYK(Human)
Calithera Biosciences

US Patent
LigandPNGBDBM620252(US20230295171, Example 122 | US20230295171, Exampl...)
Affinity DataIC50: 631nMAssay Description:YK protein is prepared from cDNA encoding human spleen tyrosine kinase and is expressed in insect cells using a baculovirus expression vector. The cD...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2023
Entry Details
US Patent