BDBM620263 US20230295171, Example 123

SMILES Cc1ccc(s1)-c1nc(N[C@@H]2CCOC[C@@H]2N)c(F)c2CNC(=O)c12

InChI Key InChIKey=UACMJLWTOXKNPO-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 620263   

TargetTyrosine-protein kinase SYK(Human)
Calithera Biosciences

US Patent
LigandPNGBDBM620263(US20230295171, Example 123)
Affinity DataIC50: 7.94nMAssay Description:YK protein is prepared from cDNA encoding human spleen tyrosine kinase and is expressed in insect cells using a baculovirus expression vector. The cD...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2023
Entry Details
US Patent