BDBM620317 3-(((2R,3R,4S,5R,6R)-4-(4-(4-chloro-2,3-difluorophenyl)-1H-1,2,3-triazol-1- yl)-5-hydroxy-6-(hydroxymethyl)-3-methoxytetrahydro-2H-pyran-2-yl)methyl)- 1-oxa-2-azaspiro[4.5]dec-2-ene-8-carbonitrile::US20230295182, Example 1.49

SMILES CO[C@H]1[C@@H](CC2=NOC3(C2)CCC(CC3)C#N)O[C@H](CO)[C@H](O)[C@@H]1n1cc(nn1)-c1ccc(Cl)c(F)c1F

InChI Key InChIKey=OCUNPGREBQDCJL-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 620317   

TargetGalectin-3(Human)
Idorsia Pharmaceuticals

US Patent
LigandPNGBDBM620317(US20230295182, Example 1.49 | 3-(((2R,3R,4S,5R,6R)...)
Affinity DataIC50: 110nMAssay Description:Briefly, compounds are serially diluted in DMSO (working dilutions). ASF-coated 384 well plates are supplemented with 22.8 uL/well of biotinylated hG...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2023
Entry Details
US Patent

TargetGalectin-1(Human)
Idorsia Pharmaceuticals

US Patent
LigandPNGBDBM620317(US20230295182, Example 1.49 | 3-(((2R,3R,4S,5R,6R)...)
Affinity DataIC50: 1.20E+3nMAssay Description:Briefly, compounds are serially diluted in DMSO (working dilutions). ASF-coated 384 well plates are supplemented with 22.8 uL/well of biotinylated hG...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2023
Entry Details
US Patent