BDBM620333 (2R,3R,4S,5R,6R)-4-(4-(4-chloro-2,3-difluorophenyl)-1H-1,2,3-triazol-1-yl)-2- (hydroxymethyl)-6-(((5s,8S)-8-(2-hydroxypropan-2-yl)-1-oxa-2- azaspiro[4.5]dec-2-en-3-yl)methyl)-5-methoxytetrahydro-2H-pyran-3-ol::US20230295182, Example 1.65

SMILES CO[C@H]1[C@@H](CC2=NO[C@]3(C2)CC[C@@H](CC3)C(C)(C)O)O[C@H](CO)[C@H](O)[C@@H]1n1cc(nn1)-c1ccc(Cl)c(F)c1F

InChI Key InChIKey=DSCVOJQITCBURE-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 620333   

TargetGalectin-3(Human)
Idorsia Pharmaceuticals

US Patent
LigandPNGBDBM620333(US20230295182, Example 1.65 | (2R,3R,4S,5R,6R)-4-(...)
Affinity DataIC50: 120nMAssay Description:Briefly, compounds are serially diluted in DMSO (working dilutions). ASF-coated 384 well plates are supplemented with 22.8 uL/well of biotinylated hG...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2023
Entry Details
US Patent

TargetGalectin-1(Human)
Idorsia Pharmaceuticals

US Patent
LigandPNGBDBM620333(US20230295182, Example 1.65 | (2R,3R,4S,5R,6R)-4-(...)
Affinity DataIC50: 2.70E+3nMAssay Description:Briefly, compounds are serially diluted in DMSO (working dilutions). ASF-coated 384 well plates are supplemented with 22.8 uL/well of biotinylated hG...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2023
Entry Details
US Patent