BDBM620349 (2R,3R,4S,5R,6R)-6-((4'H-spiro[bicyclo[2.2.1]heptane-2,5'-isoxazol]-3'- yl)methyl)-4-(4-(2,3-difluoro-4-methylphenyl)-1H-1,2,3-triazol-1-yl)-2- (hydroxymethyl)-5-methoxytetrahydro-2H-pyran-3-ol::US20230295182, Example 1.81

SMILES CO[C@H]1[C@@H](CC2=NOC3(CC4CCC3C4)C2)O[C@H](CO)[C@H](O)[C@@H]1n1cc(nn1)-c1ccc(C)c(F)c1F

InChI Key InChIKey=NQJQOFYVICPNOL-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 620349   

TargetGalectin-3(Human)
Idorsia Pharmaceuticals

US Patent
LigandPNGBDBM620349(US20230295182, Example 1.81 | (2R,3R,4S,5R,6R)-6-(...)
Affinity DataIC50: 60nMAssay Description:Briefly, compounds are serially diluted in DMSO (working dilutions). ASF-coated 384 well plates are supplemented with 22.8 uL/well of biotinylated hG...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2023
Entry Details
US Patent

TargetGalectin-1(Human)
Idorsia Pharmaceuticals

US Patent
LigandPNGBDBM620349(US20230295182, Example 1.81 | (2R,3R,4S,5R,6R)-6-(...)
Affinity DataIC50: 2.37E+3nMAssay Description:Briefly, compounds are serially diluted in DMSO (working dilutions). ASF-coated 384 well plates are supplemented with 22.8 uL/well of biotinylated hG...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2023
Entry Details
US Patent