BDBM620358 N-((5r,8R)-3-(((2R,3R,4S,5R,6R)-5-hydroxy-6-(hydroxymethyl)-3-methoxy-4- (4-(2,3,4-trifluorophenyl)-1H-1,2,3-triazol-1-yl)tetrahydro-2H-pyran-2- yl)methyl)-1-oxa-2-azaspiro[4.5]dec-2-en-8-yl)acetamide::US20230295182, Example 2.08

SMILES CO[C@H]1[C@@H](CC2=NO[C@@]3(C2)CC[C@@H](CC3)NC(C)=O)O[C@H](CO)[C@H](O)[C@@H]1n1cc(nn1)-c1ccc(F)c(F)c1F

InChI Key InChIKey=SGXPQXIOPRJCGN-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 620358   

TargetGalectin-3(Human)
Idorsia Pharmaceuticals

US Patent
LigandPNGBDBM620358(US20230295182, Example 2.08 | N-((5r,8R)-3-(((2R,3...)
Affinity DataIC50: 52nMAssay Description:Briefly, compounds are serially diluted in DMSO (working dilutions). ASF-coated 384 well plates are supplemented with 22.8 uL/well of biotinylated hG...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2023
Entry Details
US Patent

TargetGalectin-1(Human)
Idorsia Pharmaceuticals

US Patent
LigandPNGBDBM620358(US20230295182, Example 2.08 | N-((5r,8R)-3-(((2R,3...)
Affinity DataIC50: 310nMAssay Description:Briefly, compounds are serially diluted in DMSO (working dilutions). ASF-coated 384 well plates are supplemented with 22.8 uL/well of biotinylated hG...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2023
Entry Details
US Patent