BDBM620370 (2R,3R,4S,5R,6R)-6-(((5r,8R)-8-((2,2-difluoroethyl)amino)-1-oxa-2- azaspiro[4.5]dec-2-en-3-yl)methyl)-2-(hydroxymethyl)-5-methoxy-4-(4-(3,4,5- trifluorophenyl)-1H-1,2,3-triazol-1-yl)tetrahydro-2H-pyran-3-ol::US20230295182, Example 2.20

SMILES CO[C@H]1[C@@H](CC2=NO[C@@]3(C2)CC[C@@H](CC3)NCC(F)F)O[C@H](CO)[C@H](O)[C@@H]1n1cc(nn1)-c1cc(F)c(F)c(F)c1

InChI Key InChIKey=CHQYNMPKYWCNKZ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 620370   

TargetGalectin-3(Human)
Idorsia Pharmaceuticals

US Patent
LigandPNGBDBM620370(US20230295182, Example 2.20 | (2R,3R,4S,5R,6R)-6-(...)
Affinity DataIC50: 110nMAssay Description:Briefly, compounds are serially diluted in DMSO (working dilutions). ASF-coated 384 well plates are supplemented with 22.8 uL/well of biotinylated hG...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2023
Entry Details
US Patent

TargetGalectin-1(Human)
Idorsia Pharmaceuticals

US Patent
LigandPNGBDBM620370(US20230295182, Example 2.20 | (2R,3R,4S,5R,6R)-6-(...)
Affinity DataIC50: 1.80E+3nMAssay Description:Briefly, compounds are serially diluted in DMSO (working dilutions). ASF-coated 384 well plates are supplemented with 22.8 uL/well of biotinylated hG...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2023
Entry Details
US Patent