BDBM620376 2-(((2R,3R,4S,5R,6R)-2-((1-oxa-2-azaspiro[4.5]dec-2-en-3-yl)methyl)-5- hydroxy-6-(hydroxymethyl)-4-(4-(3,4,5-trifluorophenyl)-1H-1,2,3-triazol-1- yl)tetrahydro-2H-pyran-3-yl)oxy)acetic acid::US20230295182, Example 2.26

SMILES OC[C@H]1O[C@H](CC2=NOC3(C2)CCCCC3)[C@H](OCC(O)=O)[C@H]([C@H]1O)n1cc(nn1)-c1cc(F)c(F)c(F)c1

InChI Key InChIKey=UEMNPBATOBHIIG-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 620376   

TargetGalectin-3(Human)
Idorsia Pharmaceuticals

US Patent
LigandPNGBDBM620376(US20230295182, Example 2.26 | 2-(((2R,3R,4S,5R,6R)...)
Affinity DataIC50: 90nMAssay Description:Briefly, compounds are serially diluted in DMSO (working dilutions). ASF-coated 384 well plates are supplemented with 22.8 uL/well of biotinylated hG...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2023
Entry Details
US Patent

TargetGalectin-1(Human)
Idorsia Pharmaceuticals

US Patent
LigandPNGBDBM620376(US20230295182, Example 2.26 | 2-(((2R,3R,4S,5R,6R)...)
Affinity DataIC50: 3.50E+3nMAssay Description:Briefly, compounds are serially diluted in DMSO (working dilutions). ASF-coated 384 well plates are supplemented with 22.8 uL/well of biotinylated hG...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2023
Entry Details
US Patent