BDBM620450 (S)-5-((1-(difluoromethyl)-5-methyl-1H-pyrazol-4-yl)ethynyl)-N-(2-hydroxy-3-phenylpropyl)-N-methylnicotinamide::US11767310, Example 26

SMILES CN(C[C@@H](O)Cc1ccccc1)C(=O)c1cncc(c1)C#Cc1cnn(C(F)F)c1C

InChI Key InChIKey=NTZOFQTYSSUYEN-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 620450   

LigandPNGBDBM620450((S)-5-((1-(difluoromethyl)-5-methyl-1H-pyrazol-4-y...)
Affinity DataIC50: 1.80nMAssay Description:A fluorescent probe containing an Oregon green fluorophore was synthesized from a compound known to bind to RIPK1.The assay was performed in a buffer...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/2/2023
Entry Details
US Patent