BDBM620542 (R)-5-chloro-N-(2-(2,3-dihydroxypropoxy) pyridin-4-yl)-2-(4-fluoro-2-methylphenoxy)-4-(trifluoromethyl) benzamide::US20230303497, Example 114

SMILES Cc1cc(F)ccc1Oc1cc(c(Cl)cc1C(=O)Nc1ccnc(OC[C@H](O)CO)c1)C(F)(F)F

InChI Key InChIKey=BVUIFIBGHGTJFI-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 620542   

TargetPotassium voltage-gated channel subfamily H member 2(Human)
Chengdu Hyperway Pharmaceuticals

US Patent
LigandPNGBDBM620542((R)-5-chloro-N-(2-(2,3-dihydroxypropoxy) pyridin-4...)
Affinity DataIC50: 2.23E+4nMAssay Description:The reagents are purchased from Sigma (St. Louis, MO) except NaOH and KOH for acid-base titration. Final concentrations of tested solutions are prepa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/6/2023
Entry Details
US Patent