BDBM620729 1-(6-chloro-2-{[1-(2-hydroxy-2- methylpropyl)-1H-pyrazol-4-yl] amino}quinazolin-7-yl)piperidin- 4-ol::US20230303540, Example Ex-3.10

SMILES CC(C)(O)Cn1cc(Nc2ncc3cc(Cl)c(cc3n2)N2CCC(O)CC2)cn1

InChI Key InChIKey=VJARMDAWCFHKRV-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 620729   

TargetLeucine-rich repeat serine/threonine-protein kinase 2(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM620729(1-(6-chloro-2-{[1-(2-hydroxy-2- methylpropyl)-1H-p...)
Affinity DataIC50: 0.407nMAssay Description:The LRRK2 kinase activity reported herein as IC50 values was determined with LanthaScreen technology from Life Technologies Corporation (Carlsbad, CA...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/6/2023
Entry Details
US Patent