BDBM620730 1-(6-chloro-2-{[5-chloro-1-(2- hydroxy-2-methylpropyl)-1H- pyrazol-4-yl]amino}quinazolin- 7-yl)piperidin-4-ol::US20230303540, Example Ex-3.11

SMILES CC(C)(O)Cn1ncc(Nc2ncc3cc(Cl)c(cc3n2)N2CCC(O)CC2)c1Cl

InChI Key InChIKey=DUDNVDXVENWERW-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 620730   

TargetLeucine-rich repeat serine/threonine-protein kinase 2(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM620730(1-(6-chloro-2-{[5-chloro-1-(2- hydroxy-2-methylpro...)
Affinity DataIC50: 0.488nMAssay Description:The LRRK2 kinase activity reported herein as IC50 values was determined with LanthaScreen technology from Life Technologies Corporation (Carlsbad, CA...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/6/2023
Entry Details
US Patent