BDBM621007 4-(benzothiazole-6-yl)-5-fluoro-N-(5-(piperazine-1-ylmethyl)pyridine-2-yl)pyrimidine-2-amine hydrochloride::US20230303553, Example 4

SMILES Fc1cnc(Nc2ccc(CN3CCNCC3)cn2)nc1-c1ccc2ncsc2c1

InChI Key InChIKey=OMBKCNXYXFKPAO-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 621007   

TargetCyclin-dependent kinase 6(Human)
Jiangsu Tasly Diyi Pharmaceutical

US Patent
LigandPNGBDBM621007(US20230303553, Example 4 | 4-(benzothiazole-6-yl)-...)
Affinity DataIC50: 268nMAssay Description:Table 1: In the test plate, protein kinase, Ulight-labeled polypeptide substrate, ATP, and the compounds were mixed and the reaction was incubated. E...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/6/2023
Entry Details
US Patent