BDBM621041 6-(5-fluoro-2-((5-(piperazine-1-ylmethyl)pyridine-2-yl)amino)pyrimidine-4-yl)-N,N-dimethylbenzothiazole-2-amine hydrochloride::US20230303553, Example 33

SMILES CN(C)c1nc2ccc(cc2s1)-c1nc(Nc2ccc(CN3CCNCC3)cn2)ncc1F

InChI Key InChIKey=RXPRUWAATMHULG-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 621041   

TargetCyclin-dependent kinase 6(Human)
Jiangsu Tasly Diyi Pharmaceutical

US Patent
LigandPNGBDBM621041(US20230303553, Example 33 | 6-(5-fluoro-2-((5-(pip...)
Affinity DataIC50: 59nMAssay Description:Table 1: In the test plate, protein kinase, Ulight-labeled polypeptide substrate, ATP, and the compounds were mixed and the reaction was incubated. E...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/6/2023
Entry Details
US Patent