BDBM621045 US20230303553, Example 52::tert-butyl 4-(6-((4-(2-(diethylamino)benzothiazole-6-yl)-5-fluoropyrimidine-2-yl) amino)pyridine-3-yl)piperazine- 1 -carboxylate

SMILES CCN(CC)c1nc2ccc(cc2s1)-c1nc(Nc2ccc(cn2)N2CCN(CC2)C(=O)OC(C)(C)C)ncc1F

InChI Key InChIKey=MVSOCCKVJJXAJQ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 621045   

TargetDual specificity tyrosine-phosphorylation-regulated kinase 2(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM621045(US20230303553, Example 52 | tert-butyl 4-(6-((4-(2...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of DYRK2 (unknown origin) incubated for 120 mins in presence of 33P-ATPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/21/2024
Entry Details
PubMed
TargetCyclin-dependent kinase 6(Human)
Jiangsu Tasly Diyi Pharmaceutical

US Patent
LigandPNGBDBM621045(US20230303553, Example 52 | tert-butyl 4-(6-((4-(2...)
Affinity DataIC50: 1.00E+4nMAssay Description:Table 1: In the test plate, protein kinase, Ulight-labeled polypeptide substrate, ATP, and the compounds were mixed and the reaction was incubated. E...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/6/2023
Entry Details
US Patent