BDBM621047 (6-((4-(2-(dimethylamino)benzothiazole-6-yl)-5-fluoropyrimidine-2-yl)amino)pyridine-3-yl)(piperazine-1-yl)ketone hydrochloride::US20230303553, Example 35

SMILES CN(C)c1nc2ccc(cc2s1)-c1nc(Nc2ccc(cn2)C(=O)N2CCNCC2)ncc1F

InChI Key InChIKey=OSFWNAAFYPRMNV-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 621047   

TargetCyclin-dependent kinase 6(Human)
Jiangsu Tasly Diyi Pharmaceutical

US Patent
LigandPNGBDBM621047(US20230303553, Example 35 | (6-((4-(2-(dimethylami...)
Affinity DataIC50: 41nMAssay Description:Table 1: In the test plate, protein kinase, Ulight-labeled polypeptide substrate, ATP, and the compounds were mixed and the reaction was incubated. E...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/6/2023
Entry Details
US Patent