BDBM621059 US20230303556, Example 102 from WO2021/055744

SMILES CN1CCN(CC1)c1cc(cc2n(ncc12)-c1nnc(s1)C(F)F)S(=O)(=O)NC1(CC1)C#N

InChI Key InChIKey=HSUYGYRHWBTUHR-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 621059   

TargetPoly(ADP-ribose) glycohydrolase(Human)
Ideaya Biosciences

US Patent
LigandPNGBDBM621059(US20230303556, Example 102 from WO2021/055744)
Affinity DataEC50:  201nMAssay Description:PARG enzyme was incubated with compound or vehicle (DMSO) and the biotinylated-PARylated PARP-1 substrate in a microtiter plate. After adding detecti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/6/2023
Entry Details
US Patent