BDBM621061 US20230303556, Example 43 from WO2021/055744

SMILES CN(C)C(=O)N1CCN(CC1)c1cc(cc2n(ncc12)-c1nnc(s1)C(F)F)S(=O)(=O)NC1(CC1)C#N

InChI Key InChIKey=DWUCZVBUKVSTGP-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 621061   

TargetPoly(ADP-ribose) glycohydrolase(Human)
Ideaya Biosciences

US Patent
LigandPNGBDBM621061(US20230303556, Example 43 from WO2021/055744)
Affinity DataEC50:  6.60nMAssay Description:PARG enzyme was incubated with compound or vehicle (DMSO) and the biotinylated-PARylated PARP-1 substrate in a microtiter plate. After adding detecti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/6/2023
Entry Details
US Patent