BDBM621498 US11773078, Example 250

SMILES COCCN1CCN(CC1)c1ccc(Oc2cc(CN3CCC(CNC(C)=O)CC3)cc(n2)-c2cc(Cl)cc(Cl)c2)cn1

InChI Key InChIKey=AUPHEGBHBGKBKL-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 621498   

TargetFurin [108-574](Human)
Glaxosmithkline Intellectual Property Development

US Patent
LigandPNGBDBM621498(US11773078, Example 250)
Affinity DataIC50: 1.26nMAssay Description:Reactions were performed in black 384-well polystyrene low volume plates (Greiner). Furin (108-574-Tev-Flag-His) enzyme was expressed and purified fr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2023
Entry Details
US Patent

TargetFurin(Human)
National Clinical Research Center for Geriatrics

Curated by ChEMBL
LigandPNGBDBM621498(US11773078, Example 250)
Affinity DataIC50: 1.30nMAssay Description:Inhibition of furin (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed