BDBM621787 US20230312522, Compound 53

SMILES Cc1ccc(CC2(F)CCN(CC2)C(=O)c2cccnc2-c2ccncn2)cn1

InChI Key InChIKey=AYRPOLMSIHDOKG-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 621787   

TargetCholesterol 24-hydroxylase(Human)
Sage Therapeutics

US Patent
LigandPNGBDBM621787(US20230312522, Compound 53)
Affinity DataIC50: 550nMAssay Description:Briefly, in a 384-well plate format, 10 uL per well of an enzyme-substrate mixture of CYP46A1 (5 uM final concentration) and Testosterone (10 mM fina...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/13/2023
Entry Details
US Patent