BDBM622006 US20230312542, Example 74

SMILES COc1ccc(-c2[nH]c([C@@H]3C[C@@H](O)CN3C(=O)C(c3cc(OC)no3)C(C)C)nc2C(F)(F)F)cc1

InChI Key InChIKey=IJTAXKXBKUDDDL-UHFFFAOYSA-N

Data  1 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 622006   

Targetvon Hippel-Lindau disease tumor suppressor(Human)
Mitsubishi Tanabe Pharma

US Patent
LigandChemical structure of BindingDB Monomer ID 622006BDBM622006(US20230312542, Example 74)
Affinity DataKd:  5.50E+3nMAssay Description:As the device, Biacore T200 (manufactured by GE Healthcare) was used. VHL was obtained by co-expressing Elongin B and Elongin C with a Twin-Strep-tag...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/13/2023
Entry Details
US Patent