BDBM622029 US20230312542, Example 144

SMILES COc1cc(C(C(=O)N2C[C@H](O)C[C@H]2c2nc(C(=O)N3CCC(c4ccc(C)cn4)CC3)c[nH]2)C(C)C)on1

InChI Key InChIKey=PFWQPQBISOYUHO-UHFFFAOYSA-N

Data  1 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 622029   

Targetvon Hippel-Lindau disease tumor suppressor(Human)
Mitsubishi Tanabe Pharma

US Patent
LigandChemical structure of BindingDB Monomer ID 622029BDBM622029(US20230312542, Example 144)
Affinity DataKd:  5.50E+3nMAssay Description:As the device, Biacore T200 (manufactured by GE Healthcare) was used. VHL was obtained by co-expressing Elongin B and Elongin C with a Twin-Strep-tag...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/13/2023
Entry Details
US Patent